Structural biology powerfully provides concrete visuals: how a small molecule engages its protein target, how an antibody binds its cognate antigen, how biomolecular complexes assemble. These pictures can stimulate scientific creativity, support confident decision making, and fast-track projects.
Opilio's founder, Jeremiah Joseph, has 23 years of post-PhD experience, spanning structural biology, protein science, in vitro pharmacology, and management (people/data/projects/CROs); all this acquired in pharma, biotech, and academia.
Opilio offers his on-demand expertise to manage and enable in-house and outsourced projects on a fractional FTE basis: a cost-effective, win-win arrangement that keeps critical IP closer to home.
Services
DESIGN
• Design structure projects for experimental success • Incorporate wider scientific context & goals of project team • Leverage broad drug discovery experience • Provide scientific & strategic value
DRIVE
• Manage in-house & outsourced gene-to-structure projects • Handle CRO interactions: expert point of contact between project team & CRO • Troubleshoot all steps from construct design to data collection • Enable progress with hands-on structure data analysis (processing, solution, refinement)
DELIVER
• Solve & refine X-ray & CryoEM structures • Communicate results with holistic project context • Limit external exposure of critical IP (identity of protein targets & ligands) • Provide efficient & economical service through fractional FTE model
